Zantac Research Today is a free monthly online journal that collates and summarizes the latest research about Zantac, including details on ranitidine, side-effects, allergic reactions, information.

Anaphylactic reaction associated with Ranitidine in a patient with acute pancreatitis: a case report.

Rethnam U, Yesupalan RS

ABSTRACT: Ranitidine is a widely used drug and is known to be well tolerated. This case report illustrates a severe anaphylactic reaction after a single intravenous dose of 50mgs of ranitidine and highlights this unusual but life threatening adverse reaction. The patient A 56 year old female with acute pancreatitis and a known allergy to metronidazole and buscopan developed an anaphylaxis few minutes following the injection of ranitidine for epigastric discomfort. She went on to develop anaphylactic shock and a cardiorespiratory arrest. Management She was managed with adrenaline, hydrocortisone and ventilatory support following which she had a full recovery. CONCLUSION: Awareness of this rare but life threatening adverse reaction to a commonly used drug can avoid being caught unaware.

Published 3 September 2007 in J Med Case Reports, 1(1): 75.
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