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Drug eruption caused by ranitidine hydrochloride (Zantac) which showed a strong reaction in a drug-induced lymphocyte stimulation test.

Okamoto O, Fujiwara S

Department of Anatomy, Biology and Medicine (Dermatology), Faculty of Medicine, Oita University, Hasama-machi, Yufu-shi, Oita, Japan.

An 80-year-old male who developed a generalized papular erythema-type drug eruption after being treated with ranitidine hydrochloride is herein reported. The duration from the intake of the medicine to the onset of the eruption was 3 days, and the eruption remained unchanged for a week after withdrawal of the medicine and even after the eruption itself was treated. A diagnosis of drug eruption by ranitidine hydrochloride was confirmed based on a strongly-positive reaction of a drug-induced lymphocyte stimulation test (DLST).

Published 5 January 2007 in J Dermatol, 34(1): 74-9.
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