Zantac Research Today is a free monthly online journal that collates and summarizes the latest research about Zantac, including details on ranitidine, side-effects, allergic reactions, information.

Effectiveness of antiinfectives.

McLoughlin R, O'Morain C

Adelaide and Meath Hospital, and Trinity College, Dublin, Ireland.

BACKGROUND: Helicobacter pylori is one of the most common infections of mankind, with persistent colonization causing significant morbidity and mortality. TREATMENT: First-line therapy, consisting of 7-day treatment with a proton pump inhibitor or ranitidine bismuth citrate, amoxicillin and clarithromycin, with second-line therapy, consisting of a proton pump inhibitor, bismuth, metronidazole, and tetracycline, in the case of failure, is chosen as the most cost-effective method of H. pylori eradication. CONCLUSION: The effectiveness of these antiinfectives is limited by lack of compliance with treatment regimens, and increasing antibiotic resistance.

Published 24 August 2005 in Chemotherapy, 51(5): 243-6.
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